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adaptogenStrong EvidenceVegetarian

Ashwagandha

An ancient Ayurvedic adaptogen (Withania somnifera) with strong modern clinical evidence for stress reduction, sleep improvement, and testosterone support.

SW
SupplementWise Research Team

Pharmacists & Nutrition Researchers · Updated March 2026

300–600 mg

Dosage

evening

Timing

Strong

Evidence

3 cited

Studies

Benefits of Ashwagandha

Reduces cortisol and perceived stress

Improves sleep quality and onset

May increase testosterone in men

Supports muscle strength and recovery

May reduce anxiety symptoms

How Ashwagandha Works

Ashwagandha modulates the HPA axis, reducing cortisol output. Its withanolides interact with GABA receptors, promoting calmness. It also has mild thyroid-stimulating effects and may increase DHEA-S levels.

Recommended Dosage

Daily dosage range300600 mg
Best time to takeevening

Use standardized root extract (KSM-66 or Sensoril). Take with food for better absorption. Full-spectrum root extract is preferred over leaf extracts.

Who Should Avoid Ashwagandha

Pregnancy and breastfeeding
Hyperthyroidism or thyroid medication
Autoimmune conditions (may stimulate immune system)
Surgery (stop 2 weeks before)

Key Research

Adaptogenic and anxiolytic effects of ashwagandha root extract (2019)

300mg twice daily reduced stress scores by 44% vs placebo

DOI: 10.7759/cureus.9434

Effects of ashwagandha on sleep quality (2021)

600mg/day improved sleep quality by 72% in insomnia patients

DOI: 10.1371/journal.pone.0257843

Ashwagandha supplementation and testosterone (2019)

Increased testosterone by 14.7% in overweight men aged 40-70

DOI: 10.1016/j.heliyon.2019.e01640

Recommended Ashwagandha Brands in India

⭐ Best QualityTop-rated, third-party tested picks
Best Pickcapsule60 servings

Rasayanam Ashwagandha KSM-66

Rasayanam

4.4 (9,800 reviews)
FSSAI GMPThird-Party TestedLabel Verified

"Clinically validated KSM-66 extract with high standardisation (5% withanolides) from a trusted Indian nutraceutical brand."

💰 Value PickBudget-friendly alternative
Value Pickcapsule60 servings

Himalaya Ashwagandha

Himalaya

4.3 (52,000 reviews)
FSSAI GMPLabel Verified

"India's most-trusted Ayurvedic brand. Not KSM-66 standardized, but a reliable and widely available Ashwagandha at a very accessible price."

Products are selected based on quality, testing, and purity — not affiliate economics. See our selection criteria.

Works Well With

Frequently Asked Questions

What is Ashwagandha used for?

An ancient Ayurvedic adaptogen (Withania somnifera) with strong modern clinical evidence for stress reduction, sleep improvement, and testosterone support.

What is the recommended dosage of Ashwagandha?

The clinically studied dosage range is 300–600 mg per day. Use standardized root extract (KSM-66 or Sensoril). Take with food for better absorption. Full-spectrum root extract is preferred over leaf extracts.

When is the best time to take Ashwagandha?

Ashwagandha is best taken in the evening. Use standardized root extract (KSM-66 or Sensoril). Take with food for better absorption. Full-spectrum root extract is preferred over leaf extracts.

Is Ashwagandha safe?

Ashwagandha is generally considered safe at recommended dosages. However, it may be contraindicated for: Pregnancy and breastfeeding, Hyperthyroidism or thyroid medication, Autoimmune conditions (may stimulate immune system), Surgery (stop 2 weeks before). Always consult a healthcare professional before starting any supplement.

Is Ashwagandha vegetarian?

Ashwagandha supplements are available in vegetarian form. Check the specific product label for capsule ingredients.

Can I take Ashwagandha with other supplements?

Be aware of these interactions: May enhance sedative effects of sleep medications. May increase thyroid hormone levels — monitor if on thyroid meds. May lower blood sugar — monitor if on diabetes medication

Is Ashwagandha right for you?

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